She recorded a song for the Hollywood Records compilation Girl Next (2006) and another song entitled "Go to Girl" for Girl Next 2 (2007).
In 2004, Panettiere had her first starring role in the Disney Channel film Tiger Cruise.The film received mixed reviews, but she received acclaim for her role and was considered to be a highlight. In 2012, The Forger, in which she played the role of Amber, was released direct to DVD (both this and Hoodwinked Too! Panettiere voiced Kairi in Kingdom Hearts and Kingdom Hearts II.The same year she replaced Anne Hathaway as the voice of Red for the animated sequel Hoodwinked Too! She was replaced by Alyson Stoner in Kingdom Hearts Re: Chain of Memories and Kingdom Hearts 358/2 Days, but she reprised her role in Kingdom Hearts Birth by Sleep and also voiced Xion in Kingdom Hearts 3D: Dream Drop Distance.In 2004, she recorded a song entitled "My Hero Is You" with a video for the Disney Channel film she starred in, Tiger Cruise, and "Someone Like You," a duet with Watt White for another film, The Dust Factory (also with an accompanying video).The next year she recorded a song entitled "I Fly" for the Disney film Ice Princess in which she also co-starred.